Factores que influyen en la transición de insulinoterapia a antidiabético orales en pacientes con diabetes mellitus tipo 2
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Abstract
La Diabetes mellitus es una enfermedad crónica que afecta y afectará a millones de ecuatorianos. El propósito de esta investigación es identificar aquellos parámetros obtenidos de la anamnesis o de los exámenes de laboratorio que promueven la transición de insulinoterapia a antidiabéticos orales como tratamiento de mantenimiento, con el objetivo de tenerlos como referencia. La investigación se realizó en la consulta externa del Hospital de especialidades Dr. Abel Gilbert Pontón, con una muestra intencionada de 239 pacientes que reunieron los criterios de inclusión que fueron divididos en 2 grupos de acuerdo a aquellos que pudieron cambiar de insulinoterapia a antidiabéticos orales (Grupo I) 187 (78,2%) y a los que no pudieron (Grupo II) 52 (21,8%), quedando demostrado que en base a antecedentes patológicos personales de los pacientes, en especial las enfermedades nefrológicas, tipo de terapia inicial, origen del paciente (rural o urbana), edad, tiempo de evolución de la diabetes, niveles de glucosa en ayunas, hemoglobina glicosilada, glucosa postprandial, perfil renal (urea y creatinina) y colesterol pueden ser considerados como factores que influyen en la transición de insulinoterapia a antidiabéticos orales en pacientes con diabetes mellitus tipo 2.
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